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Changelog

All notable changes to MOISSCode are documented here.

v2.0.0 (February 2026)​

4 new modules, 4 expanded modules.

New Modules​

med.glucose - Diabetes & Glucose Management​

  • HbA1c estimation (ADAG), eAG conversions
  • CGM analytics: Time In Range, Glucose Management Indicator, glycemic variability
  • Insulin dosing: ISF (1800/1500 rule), carb ratio (500 rule), correction dose, basal rate, sliding scale, full regimen
  • DKA assessment and ADA hypoglycemia classification

med.chem - Medicinal Chemistry​

  • Molecular weight, Lipinski Rule of Five, BCS classification
  • ADMET screening, toxicity analysis (LD50, therapeutic index)
  • 12-drug compound database with target/class search
  • Full screening pipeline

med.signal - Biosignal Processing​

  • Heart rate from R-R intervals, HRV metrics (SDNN, RMSSD, pNN50)
  • Cardiac rhythm classification, SpO2 from photoplethysmography
  • Peak detection, moving average filter, anomaly detection
  • Respiratory rate estimation, perfusion index

med.icd - Medical Coding​

  • ICD-10-CM database (30+ codes), lookup and keyword search
  • DRG grouping (8 common DRGs), SNOMED CT mapping
  • Code validation and chapter filtering

Expanded Modules​

ModuleWhat Changed
med.scores2 -> 12 validated clinical scores (NEWS2, MELD-Na, CHA2DS2-VASc, HEART, Framingham, Child-Pugh, CURB-65, Wells PE, Glasgow-Blatchford, KDIGO AKI, APACHE II)
med.ioFull device management: monitors, ventilators, waveform capture, alarm management
med.pkTDM: renal_adjust, hepatic_adjust, therapeutic_range, trough_estimate
med.researchClinical trials: randomize, sample_size, stratify, consent_check

Documentation​

  • Full API reference for all 4 new modules
  • Rewritten docs for med.scores, med.io, med.pk, med.research
  • 2 new walkthrough examples
  • This changelog page

v1.1.0 (February 2026)​

  • Created Gotchas & Tips documentation page
  • Added 3 production-style example walkthroughs (ICU Admission, Antibiotic Stewardship, Outbreak Response)
  • AI/LLM integration guide (for-ai.md)
  • Fixed em dashes and module count inconsistencies

v1.0.0 (January 2026)​

Initial Release

  • MOISSCode language engine (lexer, parser, interpreter, type system)
  • 15 medical modules accessible via med. prefix
  • CLI tool (moiss run, moiss check, moiss fmt)
  • Python SDK with StandardLibrary class
  • 16-drug pharmacokinetic engine
  • 50+ lab tests with reference ranges
  • FHIR R4 bridge
  • KAE biomarker tracking
  • MOISS intervention timing classifier
  • Docusaurus documentation website with 5 example protocols